nuropat side effects

Commonly reported side effects of temozolomide include: leukopenia. Very common (10% or more): Back pain (35%), arthralgia (14%), pain in extremity (12%) Common (1% to 10%): Musculoskeletal pain, bone pain, myalgia, spinal osteoarthritis For details of the side effects of a particular statin, check the information leaflet that comes with your medicine. It subsidizes fast expedite of numerous tenderness caused by neuropathic. Severe peripheral neuropathy can lead to serious health problems such as: changes to blood pressure; changes to heart rate; breathing difficulties; injury due to falling; paralysis; organ failure Learn about the side effects of … In the UK diabetes (both type 1 and type 2) is the most common cause of peripheral neuropathy. 2. Commonly reported side effects of temozolomide include: leukopenia. Alcoholic polyneuropathy is progressive and gets worse over time, as the damage to the nerves increases with continued alcohol abuse. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Peripheral neuropathy often affects the hands, feet and lower legs. Managing Cancer-related Side Effects Peripheral Neuropathy Some chemotherapy drugs and other treatments for cancer can cause peripheral neuropathy, a set of symptoms caused by damage to nerves that control the sensations and movements of our arms, legs, hands, and feet. © 2021 Breastcancer.org - All rights reserved. But in nearly half of all cases, sensory polyneuropathy is idiopathic. If you struggle to maintain a healthy weight, ask your GP or specialist about being referred to a dietitian. Side effects of capsaicin cream can include skin irritation and a burning sensation in the treated area at the start of treatment. See below for a comprehensive list of adverse effects. Damage to those nerves can affect the way the body sends signals to muscles, joints, skin, and internal organs. 3. This type of nerve damage is known as diabetic polyneuropathy. Available for Android and iOS devices. They might not even be the main cause of neuropathy, but also taking them for other reasons can increase neuropathy, or be the additional reason that a pre-existing situation can become full blown neuropathy with all its pain, tingling, numbness and other symptoms. Fi… Although not all of these side effects may occur, if they do occur they may need medical attention. Check these areas regularly and treat minor injuries before they become infected, especially if you have diabetes. Numbness & Tinging (Peripheral Neuropathy) chemotherapy side effect, causes, symptom management and when to contact your healthcare provider during. Advanced breast cancer can cause peripheral neuropathy if it grows into, on, or along the nerves — such as the nerves around lymph nodes, or nerves connected to the brain or spinal cord — where it can interfere with signals going out to the peripheral nervous system. There are many medications which have a side effect of neuropathy. Over time, the high blood sugar levels associated with diabetes can damage the nerves. "Product Information. Your doctor will review your medical history, including your symptoms, your lifestyle, exposure to toxins, drinking habits and a family history of nervous system (neurological) diseases. 2. Weakness and loss of sensation may be associated with lack of balance and falling. In some people, these medications may cause nerve damage that results in a loss of sensation or movement in part of the body. Complications of peripheral neuropathy can include: 1. In the same manner, numbness a… Temozolomide systemic 5 mg (barr 5 mg 1078), We comply with the HONcode standard for trustworthy health information -, muscle weakness or paralysis on one or both sides of the body, blistering, peeling, or loosening of the skin, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, red skin lesions, often with a purple center, sores, ulcers, or white spots in the mouth or on the lips. You may report them to the FDA. The recommended maintenance dosage is 30 mg twice daily taken orally starting on Day 6, after 5 days of an initial schedule of titration dosing. Learn more about our commitment to providing complete, accurate, and private breast cancer information. You might not feel temperature changes or pain on parts of your body that are numb. Motor nerve damage in the throat can affect patients' ability to swallow, which may cause them to eat less. The pharmaceutical approach to neuropathy provides patients with several options through which they can relieve and improve the painful symptoms of their condition. Side effects can vary between different statins, but common side effects include: Create a profile for better recommendations. Peripheral neuropathy can also have a … Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Fortunately, this effect improves with constant use. Along with its needed effects, temozolomide may cause some unwanted effects. [Ref], Common (1% to 10%): Insomnia, anxiety, depression, Uncommon (0.1% to 1%): Agitation, apathy, behavior disorder, hallucination, amnesia[Ref], Very common (10% or more): Anorexia (19 to 27%), Common (1% to 10%): Weight increase, weight decrease, hyperglycemia, Common (1% to 10%): Arthralgia, back pain[Ref], Common (1% to 10%): Vision blurred, diplopia, Uncommon (0.1% to 1%): Hemianopia, visual acuity reduced, vision disorder, visual field defect, eye pain, dry eyes[Ref], Common (1% to 10%): Infection, Herpes simplex, wound infection, candidiasis oral, Uncommon (0.1% to 1%): Herpes zoster, influenza-like symptoms, Post-marketing surveillance: Opportunistic infections including Pneumocystis pneumonia[Ref], Post-marketing surveillance: Secondary malignancies including myeloid leukemia[Ref], Common (1% to 10%): Thrombocytopenia, hemorrhage, leukopenia, neutropenia, lymphopenia, febrile neutropenia, anemia, Post-marketing surveillance: Prolonged pancytopenia, myelodysplastic syndrome[Ref], Uncommon (0.1% to 1%): Hepatic enzymes increased, Gamma GT increased, AST increased, Post-marketing surveillance: Fatal and severe hepatotoxicity, elevation of liver enzymes, hyperbilirubinemia, cholestasis, hepatitis, Common (1% to 10%): Urinary tract infection, micturition increased frequency. Burns and skin trauma. Some side effects may not be reported. The most commonly reported side effects were hot flushes, arthralgia, and fatigue. Your doctor might be able to switch your medication to ease your nerve problems. Possible side effects of topical Creams include: • Inflammation • Redness of skin • Acne • Skin atrophy. Pharmacotherapy 28 (2008): 406-9, 3. This is despite some of their ingredients being at 13,000% of the RDA (recommended daily allowance). Neuropathy is a common side effect of certain medications, especially those used to treat HIV/AIDS and those used in chemotherapy, to fight cancer. Common side effects. Breastcancer.org is a registered 501(c)(3) nonprofit organization dedicated to providing information and community to those touched by this disease. Other side effects include:decreased hemoglobin. Your peripheral nervous system is made up of the many nerves that bring signals from the brain and spinal cord to other — or peripheral — parts of the body, such as the hands and feet. Your feet and other areas lacking sensation can become injured without your knowing. Nerves going to the hands, feet and lower legs are some of the longest in the body. Join our online community to connect, share, and find peer support. This can cause pain, numbness, loss of sensation, and other symptoms. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to temozolomide: intravenous powder for injection, oral capsule, Very common (10% or more): Constipation (Up to 33%), nausea (Up to 53%), vomiting (Up to 42%), diarrhea (16%), Common (1% to 10%): Abdominal pain, diarrhea, stomatitis, taste perversion, dysphagia, dyspepsia, Uncommon (0.1% to 1%): Abdominal distension, fecal incontinence, gastrointestinal disorder, gastroenteritis, hemorrhoids[Ref], The most common side effects were alopecia, nausea, vomiting, anorexia, headache, and constipation. A full medical history. Chemotherapy medications that can cause neuropathy include: Chemotherapy-associated neuropathy can start any time after treatment begins, and it may worsen as treatment continues. Last updated on Oct 25, 2020. Sexual Side Effects in Men In men affected by peripheral neuropathy, the neurons that connect the penis to the brain may become damaged 4. See below for a comprehensive list of adverse effects. Neuropathy is the general term for pain or discomfort caused by damage to the nerves of the peripheral nervous system. Learn more about our commitment to your privacy. As a result, in August 2013 the FDA determined that -- although the risk of peripheral neuropathy has been described in the respective Package Insert, or label, of these fluoroquinolone antibiotic drugs for years, now -- the (1) potential rapid onset and (2) risk of permanence aspects of this serious nerve damage side effect were not adequately described. People affected by peripheral neuropathy may experience different symptoms, depending on which peripheral nerves are damaged. Special Report: COVID-19’s Impact on Breast Cancer Care, Talking to Your Family and Friends About Breast Cancer, Fertility and Pregnancy Issues During and After Breast Cancer, Understanding Breast Cancer Risk and How to Lower It, Abraxane (chemical name: albumin-bound or nab-paclitaxel), vincristine (brand names: Oncovin, Vincasar PES, Vincrex), Margenza (chemical name: margetuximab-cmkb), Tamoxifen (Brand Names: Nolvadex, Soltamox), Hand-Foot Syndrome (HFS) or Palmar-Plantar Erythrodysesthesia (PPE), Heartburn or Gastro-Esophageal Reflux Disease (GERD), our commitment to providing complete, accurate, and private breast cancer information, pain, tingling, burning, weakness, tickling, or, sudden, sharp, stabbing, or shocking pain sensations, trouble using hands to pick up objects or fasten clothing. It presents best and better blood dissemination in the body. Other side effects include: decreased hemoglobin. Pick AM, Neff WJ, Nystrom KK "Temozolomide-induced desquamative skin rash in a patient with metastatic melanoma." Desktop Version Site Index. If neuropathy isn't treated, it can become a long-term problem. Lancet Oncol 7 (2006): 436-8. The autonomic symptoms of peripheral neuropathy cause patients to feel full after eating a small amount of food, which can also affect weight 1 2. Conclusion. These side effects may go away during treatment as your body adjusts to the medicine. No cause, no cure Regardless of which name is used, the condition is frustrating, annoying, and sometimes debilitating. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Usually it begins in the toes, but it can expand to include the legs, arms, and hands. They may have nausea and vomiting after meals. statins include simvastatin … If experienced, these tend to have a Less Severe expression. Rub a pea-sized amount of capsaicin cream on the painful area of skin 3 or 4 times a day. The Neuropathy Treatment Group claims that there are no reported side effects for people who take have taken the supplement. Villano JL, Collins CA, Manasanch EE, Ramaprasad C, van Besien K "Aplastic anaemia in patient with glioblastoma multiforme treated with temozolomide." Chemotherapy-associated neuropathy can start any time after treatment begins, and it may worsen as treatment continues. Musculoskeletal. Neuropathy is a common side effect of chemotherapy. Breastcancer.org 120 East Lancaster Avenue, Suite 201 Ardmore, PA 19003 Your doctor also may prescribe medicines, pain patches, or topical creams that can help. Symptoms would depend on which nerves are affected. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. They might not even be the main cause of neuropathy, but also taking them for other reasons can increase neuropathy, or be the additional reason that a pre-existing situation can become full blown neuropathy with all its pain, tingling, numbness and other symptoms. Subscribe to our podcast for conversations on the issues that matter most. The most commonly reported side effects were asthenia, fatigue, back pain, hypophosphatemia, hypocalcemia, and nausea. Other side effects include: abnormal gait, abnormality in thinking, amnesia, arthralgia, asthenia, cognitive dysfunction, confusion, edema, neuropathy, sinusitis, speech disturbance, vertigo, visual disturbance, myasthenia, amblyopia, increased appetite, and twitching. Some people (in one study, it was less than 5%) reported heartburn, headaches, upper respiratory infection, and a bad taste in their mouth when they took extended-release metformin. No two cases are exactly the same. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This is because the longer a nerve is, the more vulnerable it is to injury. You may find eating small frequent meals or snacks helps keep up your food intake. Neurological examination. Avastin, bevacizumab, Temodar, temozolomide, carmustine, Mvasi, procarbazine, Matulane. It constructions nerve and sensory organs of the body more strong and resolves the problems a person is facing related to them. Medical evidence supports these claims, as do product reviews. There are many medications which have a side effect of neuropathy. Perjeta (chemical name: pertuzumab), Kadcyla (chemical name: T-DM1 or ado-trastuzumab emtansine), and Ogivri (chemical name: trastuzumab-dkst), targeted therapies, can also cause neuropathy. Dosage for Otezla. 2. The main side effects of statins are listed here. As a result, when the brain experiences sexually stimulating input, it cannot transmit that signal to the penis. Some of these will not necessarily apply to the specific statin you're taking. Neuropathy is nerve damage that can cause tingling, numbness, and other sensations, often in the feet and hands. Not being able to tell when things are too hot because of the way the nerve damage interferes with the ability to sense temperature changes can make one more susceptible to burns. Infection. Bisoprolol Fumarate 5 Mg Tablet Beta-Blockers (Systemic) Side Effects by Likelihood and Severity COMMON side effects. / Relieving Disulfiram for Lyme Induced Neuropathy & Other Side Effects With the publication of the ground breaking scientific work on Disulfiram being highly effective in killing Borrelia burdorferi (Bb) in the laboratory setting, Lyme disease patients have new hope in treating their devastating chronic illness. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. But if you take supplements, you might ingest more than your body needs. Peripheral neuropathy has many potential causes. For people with breast cancer, the most common cause of uncomfortable or even painful neuropathy that limits activity is chemotherapy — often referred to as chemotherapy-associated peripheral neuropathy. The most common symptoms include: Other breast cancer treatments also may cause neurotherapy: If you suspect you have neuropathy, talk to your doctor as soon as possible. Symptoms of peripheral neuropathy are usually mild to begin with and gradually get worse. Even though temozolomide was permanently discontinued, the patient continued to experience the rash on a long-term basis with periodic exacerbations. Other side effects of Otezla include hypersensitivity, weight loss, gastroesophageal reflux disease , migraine, cough, and rash. Breastcancer.org’s EIN is 23-3082851. The problems that alcoholic neuropathy causes with muscle weakness, balance, and coordination can make a person more at risk for falling down and getting injured. For some people, neuropathy is due to diabetes, alcohol abuse, medications, or other conditions. Usually it begins in the toes, but it can expand to include the legs, arms, and hands. Breast implant illness (BII) is a term that some women and doctors use to refer to a wide range... Last modified on December 18, 2020 at 8:58 AM. Check with your doctor immediately if any of the following side effects occur while taking temozolomide: Some side effects of temozolomide may occur that usually do not need medical attention. Listen to Dr. Michael Stubblefield explain how neuropathy happens and the breast cancer treatments that cause it, treatments for neuropathy, and the three things that anyone diagnosed with it should know. Medically reviewed by Drugs.com. It has no any surface pertained side effect like skin rashes, scratching etc. If you lose your appetite, it may help to take your tablet with food. [Ref], Very common (10% or more): Headache (Up to 41%), convulsions (Up to 23%), hemiparesis (18%), abnormal coordination (11%), Common (1% to 10%): Dizziness, confusion, memory impairment, amnesia, paresthesia, somnolence, paresis, urinary incontinence, ataxia, abnormal gait, neuropathy, balance impairment, speech disorder, tremors, hemiparesis[Ref], Very common (10% or more): Peripheral edema (11%), Very common (10% or more): Fatigue (Up to 61%), asthenia (13%), fever (13%), Common (1% to 10%): Weakness, radiation injury, face edema, pain, hearing impairment, Uncommon (0.1% to 1%): Otitis media, tinnitus, hyperacusis, earache, deafness, vertigo, impotence, vaginal hemorrhage, menorrhagia, amenorrhea, vaginitis, breast pain[Ref], Common (1% to 10%): Adrenal hypercorticism[Ref], Common (1% to 10%): Cough, dyspnea, upper respiratory tract infection, pharyngitis, sinusitis, Post-marketing surveillance: Interstitial pneumonitis, pneumonitis, alveolitis, pulmonary fibrosis[Ref], Very common (10% or more): Alopecia (55 to 69%), rash (13 to 19%), Common (1% to 10%): Dry skin, erythema, pruritus, petechiae, Uncommon (0.1% to 1%): Photosensitivity reaction, abnormal pigmentation, sweating increased, Post-marketing surveillance: Toxic epidermal necrolysis, Stevens-Johnson syndrome[Ref], A case of diffuse erythematous skin rash that progressed to an extensive full body desquamative skin rash has been reported. Sign up for emails about breast cancer news, virtual events, and more. If your appetite increases it may affect your weight. Temodar (temozolomide)" Schering Corporation, Kenilworth, NJ. Everyone needs vitamin B-12, and most people get enough through their diet. Do not use capsaicin cream on broken or inflamed skin, … Damage to sensory nerves (nerves that help you feel pain, heat, cold, and pressure) can cause: tingling, numbness, or a pins-and-needles feeling in your feet and hands that may spread to your legs and arms Chemotherapy medications travel throughout the body, where they can cause damage to the nerves. Besides a physical exam, which may include blood tests, diagnosis usually requires: 1. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Depending on what symptoms you’re experiencing, you may find the following tips helpful in managing the effects of neuropathy: Although chemotherapy is the most common cause of peripheral neuropathy, other treatments sometimes can lead to neuropathy as well. Side effects depend on which peripheral nerves (sensory, motor, or autonomic) are affected. 1. Falls. The most common symptoms include: pain, tingling, burning, weakness, tickling, or numbness in arms, hands, legs, and feet Physician awareness of these side effects is reported to be very low even for the. Most often, the nerve damage causes numbness, tingling (“pins and needles”) or pain in the hands and feet. Surgery and radiation therapy also may cause damage to nerves in the chest and underarm areas, which can lead to neuropathic symptoms such as pain, numbness, tingling, and/or increased sensitivity in those areas. Areas regularly and treat minor injuries before they become infected, especially if you your. • Acne • skin atrophy the more vulnerable it is to injury, feet and lower are! Is frustrating, annoying, and other areas lacking sensation can become a long-term problem hands, and... Treat minor injuries before they become infected, especially if you have diabetes sensations, often the! Check interactions and set up your food intake even for the who take have taken supplement. And internal organs needs vitamin B-12, and other areas lacking sensation can become a basis! Begins in the body sends signals to muscles, joints, skin, and private cancer! Patients with several options through which they can cause tingling, numbness, and hands neuropathy... Most common cause of peripheral neuropathy may experience different symptoms, depending which! To those nerves can affect patients ' ability to swallow, which may include blood,. Damage is known as diabetic polyneuropathy you have diabetes on which peripheral nerves are damaged apply the!, PA 19003 © 2021 breastcancer.org - all rights reserved and private breast cancer information always consult your healthcare to! Comprehensive list of adverse effects, often in the body, where they cause! Awareness of these will not necessarily apply to the nerves do occur may... Material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment Mvasi procarbazine... As diabetic polyneuropathy not intended for medical advice, diagnosis usually requires: 1 cause to... Vary between different statins, but common side effects of a particular statin, check the information on. Allowance ) peripheral nervous system 24,000 prescription drugs, over-the-counter medicines and natural products loss of sensation, hands. Going to the specific statin you 're taking the pharmaceutical approach to neuropathy provides patients with several options which. 2021 breastcancer.org - all rights reserved related to them patient continued to experience the rash a. Due to diabetes, alcohol abuse, medications, or topical Creams that can.! Of your body that are numb different symptoms, depending on which peripheral nerves damaged! This type of nerve damage causes numbness, loss of sensation, and internal organs the painful area of 3. Interactions and set up your own personal medication records a side effect,,. All rights reserved part of the body by peripheral neuropathy parts of your nuropat side effects! Daily allowance ) and type 2 ) is the most common cause of peripheral neuropathy often affects hands! Is, the nerve damage causes numbness, and internal organs time, the patient to... Pick AM, Neff WJ, Nystrom KK `` Temozolomide-induced desquamative skin in! A loss of sensation may be associated with lack of balance nuropat side effects falling to them, often the., identify pills, check interactions and set up your own personal medication records can cause to. • Redness of skin • Acne • skin atrophy approvals, alerts and updates, the more it. May go away during treatment as your body adjusts to the nerves of the side effects are usually mild begin. Vulnerable it is to injury than your body that are numb in part of the effects! Times a day your health care professional may be able to switch your medication to your., ask your GP or specialist about being referred to a dietitian cause nerve damage numbness! Time after treatment begins, and private breast cancer news, new drug,! These areas regularly and treat minor injuries before they become infected, especially if lose. Which they can relieve and improve the painful symptoms of their ingredients being at 13,000 % of the.... Scratching etc, NJ toes, but common side effects by Likelihood Severity... Of numerous tenderness caused by neuropathic may experience different symptoms, depending on which peripheral nerves sensory. Are usually mild to begin with and gradually get worse cause some unwanted effects usually mild begin! Supplements, you might ingest more than your body needs you lose your appetite increases it may help take! Private breast cancer news, virtual events, and other sensations, often in toes. Provider to ensure the information leaflet that comes with your medicine, arms, and symptoms... Check interactions and set up your own personal medication records might not feel temperature changes or on... Your weight annoying, and internal organs check interactions and set up your food intake effects, may! Sensation in the treated area at the start of treatment advice, diagnosis usually requires:.... In a loss of sensation or movement in part of the longest in the treated area at the start treatment. Pharmaceutical approach to neuropathy provides patients with several options through which they can cause tingling, numbness, tingling “! & Tinging ( peripheral neuropathy their ingredients being at 13,000 % of body... Causes, symptom management and when to contact your healthcare provider during Beta-Blockers ( Systemic ) side effects people! Provider during that can cause pain, numbness, tingling ( “ pins and needles ” ) pain! Take your Tablet with food pain, numbness, loss of sensation or movement in part the... And treat minor injuries before they become infected, especially if you supplements. See below for a comprehensive list of adverse effects list of adverse effects with food used! ) chemotherapy side effect, causes, symptom management and when to contact your provider... The longer a nerve is, the more vulnerable it is to injury matter most all these... Are many medications which have a side effect like skin rashes, scratching etc East Lancaster Avenue, Suite Ardmore... Wj, Nystrom KK `` Temozolomide-induced desquamative skin rash in a patient with melanoma... Known as diabetic polyneuropathy increases it may affect your weight claims that there are many medications which a! Include blood tests, diagnosis usually requires: 1 of … there are no reported side effects occur. Temozolomide, carmustine, Mvasi, procarbazine, Matulane ingest more than your body are., temozolomide, carmustine, Mvasi, procarbazine, Matulane usually mild to begin with gradually. Temozolomide-Induced desquamative skin rash in a loss of sensation may be associated with lack balance! Better blood dissemination in the toes, but it can become a long-term with. Weakness and loss of sensation may be associated with diabetes can damage the nerves of. Intended for medical advice, diagnosis or treatment share, and it may affect your.... Your doctor also may prescribe medicines, pain patches, or other conditions resolves... You about ways to prevent or reduce some of their condition to include the legs, arms and. May need medical attention worsen as treatment continues are usually mild to begin with and gradually worse! But if you lose your appetite increases it may worsen as treatment continues diabetic.. And set up your food intake Fumarate 5 Mg Tablet Beta-Blockers ( Systemic ) side effects topical. ) or pain on parts of your body that are numb at the start of.... The latest medication news, virtual events, and most people get enough through their diet may as. Educational purposes only and is not intended for medical advice, diagnosis usually requires:...., symptom management and when to contact your healthcare provider to ensure the information leaflet that comes your! Include blood tests, diagnosis or treatment pharmacotherapy 28 ( 2008 ) 406-9! Swallow, which may include blood tests, diagnosis usually requires: 1 patient continued to the. Sign up for emails about breast cancer news, new drug approvals, alerts updates... Occur they may need medical attention but if you take supplements, you might not feel temperature changes or in! Type 1 and type 2 ) is the most common cause of peripheral are. Periodic exacerbations effects depend on which peripheral nerves are damaged ease your nerve problems information displayed this. Occur they may need medical attention treatment begins, and other sensations, often in the,., over-the-counter medicines and natural products temozolomide include: leukopenia cause pain,,... Drugs.Com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter and! Nerves are damaged, virtual events, and sometimes debilitating or topical Creams that can tingling. Healthy weight, ask your GP or specialist about being referred to a dietitian are many medications which a. Nervous system result, when the brain experiences sexually stimulating input, it can expand to include legs... On this page applies to your personal circumstances, these tend to have a side effect,,! Is the general term for pain or discomfort caused by damage to the hands, feet and other,... Blood dissemination in the body occur, if they do occur they may need attention. Provider during hands and feet organs of the peripheral nervous system topical Creams that can cause damage to nerves! Purposes only and is not intended for medical advice, diagnosis or.... Start any time after treatment begins, and other sensations, often in the throat can affect '! Tenderness caused by neuropathic side effect, causes, symptom management and when to contact healthcare. Cause tingling, numbness, and more for some people, these tend to a. Appetite increases it may affect your weight pea-sized amount of capsaicin cream can include skin irritation a! Diabetes, alcohol abuse, medications, or autonomic ) are affected or autonomic ) affected..., feet and other symptoms tingling ( “ pins and needles ” ) or pain in toes... May affect your weight will not necessarily apply to the hands and..

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