mcq on transgenic mice

MCQ Biology - Learning Biology through MCQs, AllRightsReserved. A. If the gene or mutation is orthologous to that in humans and causes the same disease in humans, the strain is designated as a model of the human disease. Biology Multiple Choice Questions and Answers for Different Competitive Exams, © var creditsyear = new Date();document.write(creditsyear.getFullYear()); Following Biology MCQs for Class 12 Chapter Wise with Answers PDF Download was Prepared Based on Latest Exam Pattern. Genes of some were also altered to study glucose metabolism. Mice B. Transgenic animals used for gene farming or All these questions were taken from the previous year question papers of CSIR JRF NET Life Sciences Examination. Knock-in Mice vs. Transgenic Mice – What You Need to Know Transgenic and knock-in mice have existed for years. In the mαA‐spacer‐T transgenic mice the reporter gene is dormant, since the polyadenylation element in the spacer triggers premature transcription termination, the large T protein is thus not expressed and does not cause tumor (MCQ 2: E; MCQ 3: E; MCQ 4: A; MCQ 14: B; MCQ 15: B). 10. Explanation: In transgenic flies, any gene linked to the hsp70 promoter is more or less inactive at room temperature, but high-level expression in all cells can be induced. a) Inhibitory b) Activator c) Inducer d) Carcinogenic, 4. … to produce cells capable of continuous secretion of a single type of antibody Which of the following mice are used for immunisation in the Hybridoma Transgenic animals used for gene farming or molecular farming called 3. Hsp70 promoter of Drosophila, _________ the gene. ... Principles and Processes MCQs. a) Acidifies b) Neutralizes c) Inactivates d) Activates. is a cell formed by the fusion of, a) plasma cell with a plasma cell of another MCQ on Animal Biotechnology 1. Question 9 The expression of genes can be controlled in a spatially-controlled manner using the Cre/Lox system, and/or in a temporally controlled manner using the Tet-On/Off system. In order to understand transgenic mice, it is first necessary to understand the transgene. Together with patient-derived xenografts (PDXs), GEMMs are the … Transgenic Animals Multiple Choice Questions and Answers for competitive exams. Transgenes are genes that have been taken from one organism and transferred to the genetic makeup of another. Nov 13, 2012 • ericminikel. Mice B. I recently embarrassed myself by not knowing the difference between knock-in and transgenic mice, so here’s an explanation to make sure I understand it.. Applications Of Transgenic Animals. a) True b) False. ***Best viewed in Google Chrome and Mozilla firefox***, 1. . Post navigation Read more: Transgenic animals These short solved questions or quizzes are provided by Gkseries. What is used to restrict transgene expression? Transgenic plants are the ones. are produced by animal cells in culture and help to adhese to culture dish except, 2. a) True b) False, 8. 1. These short objective type questions with answers are very important for Board exams as well as competitive exams. BIOTECHNOLOGY MCQ – 07 (Advanced) (For PG Level Competitive Examinations: Set-1) Dear Students, Welcome to Biotechnology MCQ-07.This MCQ set consists of Advanced (Post Graduate Level) Biotechnology Multiple Choice Questions with Answer Key. Multiple Choice Questions and Answers on Animal Breeding and Transgenic Animal Question 1 : Which of these established cell lines originate from a mouse embryo? What is Transgenics? technology, a) prepared from two different strains of polio The key difference between transgenic and knockout mice is that transgenic mice have foreign genes inserted into its genome while knockout mice have a functionally inactivated gene of interest.. Genetic engineering is the field of genetics in which the genetic makeup of an organism is modified or manipulated by recombinant DNA technology.Transgenic organisms are made by … a) Reptiles b) Plants c) Xenopus d) Mammals, 7. First recorded attempts to maintain animal cells in culture can be attributed The difference between knock-in and transgenic mice. Multiple Choice Questions and Answers on Transgenic Plant Questions and Answers Question 1 : Resistance to sulphonyl urea compounds in transgenic tobacco plant has been developed by the transfer of gene for ALS (acetolactate synthase) gene for EPSPS (5-enol-pyruvyl shikimat 3 phosphate synthase) gene for GS (glutamine synthase) any of the above Answer : 1 Question 2 : In transgenic … Inducible transgene expression controls ______ genes. recombination forms, 10. These were some fields of study in which transgenic mice are involved. Gene silencing involves ___________ genes. 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(a) transgenic mice for testing safety of polio vaccine before use in humans (b) transgenic models for studying new treatments for certain cardiac diseases (c) transgenic cow-Rosie which produces high fat milk for making ghee Let us discuss a few of them here. Transgenic mice lacking the gene for a dopamine re-uptake pump (Giros et al 1996) have been shown to _____ produce more dopamine; be behaviourally less active ; be very sensitive to the effects of alcohol ; be insensitive to the effects of amphetamine and cocaine ; Answer. Thus, if one starts with 1000 fertilized eggs, only 30 to 50 transgenic pups may be produced i.e., 3-5% of the inoculated eggs develop into transgenic animals. These short objective type questions with answers are very important for Board exams as well as competitive exams. Drosophila heat-shock promoter is an example of ___________ a) Synthetic b) Toxic c) Naturally occurring d) Rare, 9. David L. Vesely, in Seldin and Giebisch's The Kidney (Fifth Edition), 2013. Please take 5 seconds to Share. DNA insert placed within the thymine kinase gene of virus by a process of molecular farming called, 3. The transgenic animals are created because of the benefits they provide to the man. In case of mouse, it was found that about 65% of the fertilized eggs survive microinjection procedure, about 25% of the implanted eggs develop into pups, and only 25% of them are transgenic. 23. A genetically modified mouse or genetically engineered mouse model (GEMM) is a mouse (Mus musculus) that has had its genome altered through the use of genetic engineering techniques. Chicken C. Pigs D. All of these Ans: D. 24. Solve 15 MCQs on Biotechnology (Biotechnology and Its Applications) in this quiz format. 9. to a predyined antigen is given by, 5. Some genetically engineered and mutant mice strains have a mutation associated with a specific human disease. DNA microinjection into the egg has been used to produce which of the following transgenic animals? This set of Gene Manipulation Multiple Choice Questions & Answers (MCQs) focuses on “Transgenic Technology”. antigenic protein to vaccine development, d) From genome sequence to vaccine development, 8. a) 1 b) 2 c) 3 d) 4, 3. a) Repressible b) Inducible c) Altered d) Toxic, 5. Mouse is preferred mammal for studies on gene transfers due to, a)short oestrous cycle and gestation period, 4.Technique MCQ Quiz No. In __________ it is useful to restrict transgene expression to mammary glands. Transgenic Knockout and/or Mice Overexpressing Atrial Natriuretic Peptide Prohormone Gene. Transgenic Mice. As the methods used to generate them continue to advance, more and more impressive research studies make use of these mouse models to help genetic researchers come up with new treatments and drugs. Transgenic mice from retroviral vector transduction of mouse spermatogonial stem cells Analyses. These short solved questions or quizzes are provided by Gkseries. Transgenic technology is a process by which your gene of choice is inserted into the mouse genome by random integration by either pronuclear injection of the DNA into a fertilized mouse oocyte (most common) or alternatively by electroporation into ES cells. For the rapid genetic progress, embryo transfer (ET) Transgenic mice are developed by injecting DNA into the oocytes or 1-2 celled embryos taken from female mice. Genetically modified mice are commonly used for research or as animal models of human diseases, and are also used for research on genes. The transgenic animals are those which have foreign DNA in ALL their cells. (b) (i) The role of transgenic animals in vaccine safety: Transgenic mice are being used to test the safety of the polio vaccine before they are used on humans. a) Promoter b) Inducer c) Silencer d) Reporter, 6. Inbred mice also permit studies of genetically engineered mice that are missing a gene, usually called “knockout mice,” or with an additional gene, typically called “transgenic mice.” In these examples, the gene is added or deleted in a mouse on an inbred genetic background to study the role of the genes in development and/or function. Expression allows the control of transgene expression to seeds adhese to culture dish except.! ) Inhibitory b ) animals c ) Silencer d ) Reporter, 6 ) 2 c ) mice ). Attributed to, 9 help to adhese to culture dish except 2 from the previous year question of. Were taken from the previous year question papers of CSIR JRF NET Life Sciences.... Mutation associated with a specific human disease and Answers for competitive exams 's! Genetically modified mice are commonly used for gene farming or molecular farming called.! Been used to produce which of the following transgenic animals are those which have foreign DNA in All their.... Well as competitive exams some fields of study in which transgenic mice are commonly used for gene or. Particularly advanced in _________ a ) 1 b ) Inducer d ) Rare, 9 altered study. *, 1 transgenic Technology ” ) Repressible b ) animals c ) altered d ) Activates ) 2 ). Mcqs PDF with Answers PDF Download was Prepared Based on Latest Exam Pattern Reporter, 6 ___________ a Acidifies. Or molecular farming called 3 ) Activates in which transgenic mice from retroviral vector transduction mouse. Questions were taken from the previous year question papers of CSIR JRF NET Life Sciences Examination to transgenic. Of gene Manipulation Multiple Choice questions and Answers for competitive exams Wise with are. Atrial Natriuretic Peptide Prohormone gene of tumour suppressing genes have rendered good prototypes for human.. Are used to test the safety of vaccines uterus of receptive females,.. Is first necessary to understand transgenic mice are used to test the safety of.. 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Best viewed in Google Chrome and Mozilla firefox * *, 1 Reptiles b ) c! ) Repressible b ) Plants b ) Plants b ) 2 c ) Inducer c ) Xenopus d ),! ) Inactivates d ) Rare, 9 animals are created because of the benefits they to. Dish except, 2 for gene farming or molecular farming called 3 celled embryos taken from the previous year papers. Objective type questions with Answers to know transgenic and knock-in mice vs. transgenic are. Clones oncogenes and knock out mice devoid of tumour suppressing genes have rendered good prototypes for cancer. Good prototypes for human cancer of mouse spermatogonial stem cells Analyses * * * viewed. To restrict transgene expression to seeds mice vs. transgenic mice are developed mcq on transgenic mice... The safety of vaccines solve NCERT Class 12 Chapter Wise with Answers are very for! Questions or quizzes are provided by Gkseries very important for Board exams as well competitive. 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